Beth Holloway has created the Natalee Holloway Resource Center, named for her daughter who went missing during a 2005 high school graduation trip to the Caribbean island.
The center will be based at the National Museum of Crime & Punishment in downtown Washington.
The nonprofit center aims to provide families with an action plan, examples of missing person posters, contacts, media liaisons and other services to guide families during crises.
Officials also say they will provide educational programs on safe traveling and crime prevention and encourage careers in forensic science and law enforcement. The center will launch June 8.