AAA estimates some 35.2 million people will travel more than 50 miles to a destination over this three-day weekend.
About 29.6 million of those, or 85 percent, will be doing it on the road. That's a record, about a half million more than Labor Day weekend 2005.
For that reason, among others, law enforcement will be taking special care this weekend, looking for those who might not be doing their driving the legal way.
The Mississippi Highway Patrol is anticipating that record number of travelers on the road. All time off has been canceled so the Highway Patrol can meet those drivers with more patrol presence.
Lt. Ralph Smith of Troop H says drivers can expect strict enforcement of all traffic laws. He says Mississippi is practically leading the country in auto-related fatalities.
"We are trying to decrease the fatality rate, special emphasis on road blocks looking for impaired drivers from alcohol or drugs or anything else. That's our main focus, is trying to get the impaired drivers off the road," Smith said.
Smith said drivers must be alert. Area fatality statistics show many accidents are single-car accidents where the driver ran off the road.
Many campaigns focus attention on teenage drivers, but the area statistics also show more experienced drivers ages 21 and older are actually involved in fatal accidents more often.
And there is some good news for travelers, a small break on gas prices down significantly from their near $3.00-a-gallon highs earlier this summer.
The average price of a gallon of regular unleaded in Mississippi is about $2.61, in Alabama, $2.62, and the national average is $2.76.