Lauderdale County Habitat for Humanity's Re-Store in Meridian is the 62nd of its type opened by chapters around the country.
Executive director Fonda Rush explained how money generated would be used.
"The profit from the store is to go toward helping build more houses in Lauderdale County," Rush said.
To date, Habitat has built 39 houses in Lauderdale County. The store's inventory will mainly come from donations from individuals and businesses.
"If you're 'rehabing' your house and you've got cabinets and windows and doors or you're getting new furniture and your furniture is still in good shape, you want to donate that, you can donate that," said Rush.
"You can donate to us and that will be a tax deduction."
Store manager Mark Barrett said building materials are probably the greatest need.
"Doors, windows, anything if they're doing a remodel and they've taken out those items, we'll accept those items. Ceiling tiles, acoustic tiles, leftover roofing shingles, if they have any. We'll take any of those materials," Barrett said.
"We're going to have a special place for paint that's already been mixed," Barrett added. " We'll accept those items and hopefully find a home for those, plumbing materials, used toilets and sinks, things like that, we'll take those as well."
The Habitat Re-Store is located at 2911 8th Street, the former Badcock Furniture Store.