A bill headed to Mississippi Gov. Phil Bryant says a physician would have to be present when a woman takes abortion-inducing drugs.
Senate Bill 2795 also says the woman would have to return to the doctor's office two weeks later for a follow-up examination.
Supporters say the bill is designed to prevent the practice of the drugs being administered by someone from a remote location while communicating by phone or webcam.
The Senate passed the final version of the bill 46-6 on Wednesday. The House passed it 84-30 Friday.
Republican Sen. Sally Doty of Brookhaven voted for the bill, saying she believes it will help protect women's health.
Democratic Sen. Kenny Wayne Jones of Canton voted against it, saying government shouldn't be so deeply involved in women's health decisions.