The award goes to schools whose students perform at high levels or who have made dramatic improvements in their achievement, particularly for low-income children.
The schools are: Kosciusko Middle School; Madison Station Elementary School in Madison; Nichols Elementary School in Biloxi; and Southeast Lauderdale High School.
Nichols was closed after last school year due to budget constraints and declining enrollment.
About 300 schools were recognized nationally this year. The schools will be honored Nov. 15-16 in Washington, D.C.
The award has been given out annually by the Education Department since 1982.