The 29th Avenue bridge over Sowashee Creek will be closed starting Monday, May 17.
The process of dismantling the bridge and building a new one will begin.
A detour route will be marked on the adjacent streets.
The bridge will be closed for approximately 3 to 4 months for the almost $1 million project.
Federal stimulus funds are paying for the project, with the exception of some engineering work.
The city says the new bridge will be wider, with an 8-foot shoulder on each side for better safety.
Motorists are already navigating around the 26th Avenue underpass, or "subway", which has been closed for the last two months. That project includes repairs, painting, lighting and cushioning to make the underpass lighter, brighter and safer. It's likely the new 29th Avenue bridge will be completed before the subway project.
The city says the Mississippi Department of Transportation set the schedule that resulted in both projects being under construction simultaneously.