The James O. Eastland Federal Building in downtown Jackson may be converted into apartments and commercial space.
The Clarion-Ledger reports that developers say the project would cost $20 million.
The 115,000-square-foot space has sat vacant since Aug. 1, 2011, following the opening of the new federal courthouse.
Built in 1934 by the Jackson-based architectural firm Hull and Malvaney, the courthouse replaced an earlier one built on the same property. The building also housed a post office until the post office relocated in 1988.