Mayor Frank Melton claims federal prosecutors are trying to inject race into his next criminal trial of with a proposed jury questionnaire.
The government's proposed questions include several about race relations.
Melton is just the second black mayor of Mississippi's largest city. He and his former police bodyguard are accused of orchestrating the late night sledgehammer destruction of a duplex Melton considered a crack house in August 2006.
Their third trial related to the raid is scheduled to begin May 11. The first federal trial ended in a hung jury. Melton's state trial ended with a not guilty verdict.
This time federal prosecutors persuaded the judge to bring in a jury from south Mississippi to hear the case.
Since then each side has accused the other of trying to use race to their advantage.