The East Central Republican Headquarters opened Friday in Meridian at 2120 5th Street.
Its opening is the first of several efforts by the GOP to encourage constituents to participate in the November elections.
"Get Out The Vote" chairman, Betty Lou Jones, said the goal is electing Republicans to every office, locally and statewide.
"And we want to do that with the biggest vote we've ever had in the state of Mississippi," said Jones. "We don't want people to be lulled into a sense of complacency. A lot of times that happens when you have incumbents, especially incumbent governors. But elections are won at elections and not any time other than that. And it's important for every Republican voter to vote on Nov. 6."
Jones said campaign literature and candidate signs will be available there Monday through Friday, 10:30 a.m. to 5:20 p.m., and volunteers are welcomed.