Chris Nickson threw for 200 yards and ran for 78 more and a touchdown to lead Vanderbilt to a 31-17 win over Mississippi Saturday.
Cassen Jackson-Garrison had three touchdowns and 127 yards rushing, and the Commodores (2-1) improved to 1-1 in the Southeastern Conference.
The Rebels (1-2) dropped their league opener for the fourth consecutive year. Ole Miss fell to 46-34-2 against Vanderbilt.
Brent Schaeffer relieved Seth Adams in the fourth quarter, and threw a 54-yard touchdown pass to Mike Wallace on his first attempt to narrow the score to 24-17.
Schaeffer failed to complete a pass on the following possession, and Jackson-Garrison scored for the Commodores on a short field to put the game out of reach.
Viewers with disabilities can get assistance accessing this station's FCC Public Inspection File by contacting the station with the information listed below. Questions or concerns relating to the accessibility of the FCC's online public file system should be directed to the FCC at 888-225-5322, 888-835-5322 (TTY), or firstname.lastname@example.org.